Search results for "Respiratory System Procedures"

showing 2 items of 2 documents

Evidence for pleural epithelial-mesenchymal transition in murine compensatory lung growth

2017

In many mammals, including rodents and humans, removal of one lung results in the compensatory growth of the remaining lung; however, the mechanism of compensatory lung growth is unknown. Here, we investigated the changes in morphology and phenotype of pleural cells after pneumonectomy. Between days 1 and 3 after pneumonectomy, cells expressing α-smooth muscle actin (SMA), a cytoplasmic marker of myofibroblasts, were significantly increased in the pleura compared to surgical controls (p < .01). Scanning electron microscopy of the pleural surface 3 days post-pneumonectomy demonstrated regions of the pleura with morphologic features consistent with epithelial-mesenchymal transition (EMT); nam…

MaleB VitaminsThin-Layer Chromatography0301 basic medicinePathologyOrganogenesismedicine.medical_treatmentVimentinBiochemistryMiceSpectrum Analysis Techniques0302 clinical medicineMedicine and Health SciencesElectron MicroscopyRespiratory System ProceduresPneumonectomyLungImage CytometryMicroscopyMultidisciplinarybiologyOrganic CompoundsChromatographic TechniquesQRVitaminsrespiratory systemChemistryPhenotypemedicine.anatomical_structureThoracotomySpectrophotometry030220 oncology & carcinogenesisPhysical SciencesPleuraMedicineScanning Electron MicroscopyMyofibroblastResearch Articlemedicine.medical_specialtyEpithelial-Mesenchymal TransitionImaging TechniquesScienceCompensatory growth (organ)BiotinSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesPneumonectomyFluorescence ImagingmedicineAnimalsVimentinEpithelial–mesenchymal transitionLungSurgical ExcisionFluorimetryOrganic ChemistryChemical CompoundsBiology and Life SciencesProteinsrespiratory tract diseasesMice Inbred C57BLCytoskeletal ProteinsPlanar ChromatographyB vitamins030104 developmental biologybiology.proteinMesothelial CellPLOS ONE
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Comparison of Epithor clinical national database and medico-administrative database to identify the influence of case-mix on the estimation of hospit…

2019

BackgroundThe national Epithor database was initiated in 2003 in France. Fifteen years on, a quality assessment of the recorded data seemed necessary. This study examines the completeness of the data recorded in Epithor through a comparison with the French PMSI database, which is the national medico-administrative reference database. The aim of this study was to demonstrate the influence of data quality with respect to identifying 30-day mortality hospital outliers.MethodsWe used each hospital's individual FINESS code to compare the number of pulmonary resections and deaths recorded in Epithor to the figures found in the PMSI. Centers were classified into either the good-quality data (GQD) …

MaleDatabases FactualOutliers DRGPulmonologyCancer Treatment030204 cardiovascular system & hematologyLogistic regressionHealth administration0302 clinical medicineHospital AdministrationInterquartile rangeMedicine and Health SciencesMedicineHospital MortalityRespiratory System ProceduresMultidisciplinaryMortality rateQRRegression analysisHospitals3. Good healthSurgical OncologyOncologyMedicineFemaleRisk AdjustmentLung ResectionResearch ArticleClinical OncologyDeath RatesScienceSurgical and Invasive Medical Procedures03 medical and health sciencesCase mix indexPopulation MetricsHumansDiagnosis-Related GroupsPopulation BiologySurgical Resectionbusiness.industryBiology and Life SciencesModels TheoreticalHealth CareStandardized mortality ratioLogistic ModelsDyspnea030228 respiratory systemHealth Care Facilities[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieData quality[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieClinical MedicinebusinessDemography
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